欧美成人动漫日韩国庆_亚洲天堂自拍偷拍_人妻少妇边接电话边娇喘_新婚少妇交换杨雨婷_高清不卡一区二区在线观看_亚洲国产中文另类久久久精品网站_十八禁裸体自慰免费观看_日本亚洲中文有码_日本人zzzwww色视频直播_国产福利姬在线观看

"A randomized, single-blind, placebo-controlled, single-center, single-dose-escalation, and multi-dose-escalation phase I trial evaluated the safety, tolerability, pharmacokinetic, and preliminary pharmacodynamic characteristics of subcutaneous RBD7022 in subjects with normal or elevated LDL cholesterol" is ongoing.

RBD 7022 is a GalNAc-conjugated siRNA against PCSK9 (proprotein convertase subtilisin/kexin type 9) for the treatment of hyperlipidemia by lowering LDL-C (low-density lipoprotein cholesterol). The drug reduces LDL-R (low-density lipoprotein receptor) lysosomal degradation and increases the number of LDL-R on the surface of liver cells, thus reducing LDL-C levels in the blood. 

In September 2022, the product received approval from the National Medical Products Administration (NMPA) to conduct its first in human clinical trial in China.

In April 2023, the study was initiated at the Peking Union Medical College Hospital of the Chinese Academy of Medical Sciences (Peking Union Medical College), and is currently in the multi-dose incremental enrolment phase.